The RADIAN ASAP: A Direct Analysis Mass Spectrometer

The RADIAN ASAP is Waters Corporation's latest dedicated direct analysis system that has been developed for the simple, quickand affordable MS based screeningof solids and liquids. The RADIAN ASAP has been designed to integrate provensingle quadrupole mass spectrometry technologywith the Atmospheric Pressure Solids Analysis Probe (ASAP), thus ensuring user-friendliness and quality in a compact footprint.

The single quadrupole mass detector offers high-quality mass spectral data, without requiring any specialisttraining or expertise. This avoids the need to outsource and wait for outcomes from central or contractanalytical service laboratories.

Flexible Workflow Solutions in Four Simple Steps

Performing analyses onRADIAN ASAP is easy and intuitive, enabling users to produce outcomes with little or no sample preparation. This makes it a perfect tool for laboratories to make faster, better informed decisions. The system can ionize molecules directly from a solid or liquid and is thus appropriate foran extensive range of workflows and applications.

1. Clean the capillary. Image Credit: Waters Corporation

2. Load sample onto capillary. Image Credit: Waters Corporation

3. Insert capillary to start acquisition. Image Credit: Waters Corporation

4. Real-time data visualization. Image Credit: Waters Corporation

Features

If users intend to enhance their formulation development cycle, expand their client servicesor just be more competitive with their turnaround times;using direct MS analysis that is capable of pushing several system-wide efficiencies can help achieve these operational goals.

The RADIAN ASAP integrates flexibility, ease of useand speed without requiring complicated sample preparation, separationor extensive MS experience. Thus, it helps users and their laboratory accomplish more.

Easy operation and data interpretation

Little to no sample preparation

Real-time outcomes and classification

No separation needed

Software

Software Solutions for Rapid Interpretation and Classification

LiveID Software allows the real-time classification of samples with the help of RADIAN ASAP. Information is offered to the user right at the time of analysis, thereby allowing informed, real-time decision making and eliminating doubt from sample identity.

LiveID — Authenticity Testing

LiveID makes use of statistical models to categorize samples for customers examining the authenticity, adulterationand quality of raw materials and finished formulations. Initially, authentic or verified samples are utilized to make and confirm a statistical model. Then, the validated model can be utilized with test samples to produce live classifications. The output is an easy-to-interpret yes or no answer.

Image Credit: Waters Corporation

LiveID — Library Matching

LiveID can handle real-time library matching workflows, where the software matches all compounds in the library with every sample under analysis. This offers a score out of 1000, where values near 1000 show that it is probable that the compound of interest is in the sample; lower scores denote that the compound is unlikely to be present in the sample.

Image Credit: Waters Corporation

Automated Data Processing and Reporting

OpenLynx processing offers users customizable processing abilities to produce automated mass confirmation reports in either pdf, browseror printed format.

IonLynx enables users to identify levels and relative ratios of analytes of interest in complicated samples to help decision-making in QC and formulation monitoring. IonLynx offers automated processing and reporting of non-chromatographic data sets, like those produced by RADIAN ASAP.

Applications

Chemicals and Materials

Quality control of raw materials

RADIAN ASAP and IonLynx help formulation Development Laboratories in the new polymer and specialty chemical industry to reduce costs and enhance efficiencies. RADIAN ASAP provides a complementary method to conventional materials property measurement techniques, such as rheological profiling or thermal analysis.

RADIAN ASAP enables formulation designers to easily note the main components of their advanced materials and expedite the decision-making process in formulation design. Featuressuch as thermal gradient analysisare considered to offer benefits in analysingmore complexsamples that are generally seen in the chemical sector.

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Video Credit: Waters Corporation