Spectradyne

Spectradyne’s nCS1 system, based on Microfluidic Resistive Pulse Sensing (MRPS), measures the size and concentration of nanoparticles with superior resolution.

An electrical detection method, MRPS maintains excellent sensitivity when measuring particles of high transparency, such as biological nanoparticles. Using a microfluidic-based measurement cartridge requiring only 3µL of sample, the system overcomes the limitations found with light scattering-based methods, particularly with respect to resolving polydispersity, being material-independent and being able to accurately measure concentration.

Typical applications include measurement of protein aggregation in biologics, quantification of size and concentration of nanomedicine delivery systems (such as virus, lipid nanoparticles (LNPs), and extracellular vesicles (EVs)).