Promass U 500: The Ideal Single-Use Flowmeter

The Proline Promass U 500 Coriolis flowmeter is the first single-use option for biotech applications. It offers high performance, cGMP compliance, and up to 4 I/Os.

Overview

Specs at a Glance

Max. measurement error

Mass flow (liquid): ±0.5%

Measuring range

0 to 75 kg/h (0 to 165.3 lb/min)

Medium temperature range

3 to 60 °C (37.4 to 140 °F)

Max. process pressure

6 bar (87 psi)

Wetted materials

Measuring tubes: Stainless steel 1.4435, 316 L

Hose connection nipple: Makrolon Rx 1805 polycarbonate

Premium performance and cGMP compliance with single-use flowmeter Proline Promass U 500. Image Credit: Endress+Hauser

Field of Application

The Promass U 500 is an excellent single-use flowmeter for biopharmaceutical applications in the life sciences industry. It represents a response to the transition from multi-use to single-use gadgets, as well as batch to continuous manufacturing.

Promass U 500 offers multivariable measurement, which improves reliability, precision, and industry compliance according to cGMP standards. The flowmeter is well-suited for upstream and downstream monoclonal antibody (mAb) applications.

The sensor consists of two parts: a disposable portion available in four line diameters and a permanently installed base unit that fits all line sizes. Heartbeat Technology detects the flow range and validates the factory calibration after installation.

This simplifies the commissioning process and eliminates the requirement for field calibration. The transmitter, which has a built-in web server, WLAN, and up to four I/Os, allows for easy operation as well as additional process and device information.

Benefits

Best-in-class measuring accuracy: Coriolis technology with multivariable measuring

Highest turndown ratio: One sensor accommodates all line sizes of disposables

cGMP compliance: Created according to the most recent standards and rules, complete with the necessary attributes and documentation

Simple, fast commissioning: One-handed mounting and automated calibration data transfer

Self-drainability or air bubble escape: Thanks to variable mounting angles

No field calibration needed: Automated verification using embedded Heartbeat Technology

Digital integration: Modern single-pair Ethernet-based communication methods

Specifications

Measuring/Application Task

Liquids

Measuring principle: Coriolis

Product headline

Single-use specialized for biotech applications, including a remote version supporting up to four I/Os

Modern fieldbus communication protocols (2-wire)

The life sciences industry’s best-measuring performance for liquids in single-use operations

Sensor features

One sensor fits all DN: a single variation with four disposable line sizes offers the highest turndown ratio. One-handed mounting of disposables - simple commissioning, thanks to the intuitive clamping mechanism

Mounting angle - self drainabillity or air bubble escape

Disposable manufactured from 1.4435 (316L) and polycarbonate. Completely traceable cGMP compliance. One sensor accommodates four line sizes from ¹⁄₈ to 1”

Transmitter features

Remote version supports up to four I/Os. Backlit display with touch controls and WLAN access. Standard cable connects sensor and transmitter

Access process and diagnostic information via flexible I/Os and Ethernet connectivity. Reduced complexity and variety with flexibly customizable I/O functions. Heartbeat Technology provides integrated verification

Nominal diameter range

¹⁄₈" to 1”

Wetted materials

Hose connection nipple: Makrolon Rx 1805 polycarbonate

Measuring tubes: Stainless steel 1.4435, 316 L

Measured variables

Mass, density, temperature

Max. measurement error

Mass flow (liquid): ±0.5%

Measuring range

0 to 75 kg/h (0 to 165.3 lb/min)

Max. process pressure

6 bar (87 psi)

Medium temperature range

3 to 60 °C (37.4 to 140 °F)

Ambient temperature range

5 to 40 °C (41 to 104 °F)

Transmitter housing material

Aluminum, AlSi10 Mg, coated

Degree of protection

Transmitter: IP66/67, Type 4X enclosure

Sensor: IP54

Display/Operation

Configuration through local display and operating tools is possible

4-line backlit display with touch control (operated from outside)

Outputs

4-20 mA (active/passive)

4-20 mA WirelessHART

4-20 mA HART (active/passive)

Double pulse output (active/passive)

Pulse/frequency/switch output (active/passive)

Relay output

Inputs

4-20 mA input

Status input

Digital communication

Modbus RS485, PROFINET over Ethernet-APL

Power supply

AC 100 to 230 V / DC 24 V (non-hazardous area)

Product safety

CE, C-tick, EAC marking

Functional safety

Functional safetyaccording to IEC 61508, applicable in safety-related applications in line with IEC 61511

Hygienic approvals and certificates

cGMP compliance, ASME BPE, BPOG, FDA

Smart Instrumentation Through Heartbeat Technology

The smart instrumentation range with Heartbeat Technology delivers detailed device insights, enhancing cost-efficiency and operational safety.

Xpert Selection

Image Credit: Endress+Hauser

Specialized products

Engineered for tough applications