NANOPHOX CS | The Next Generation DLS Instrument

Sympatec - a pioneerin the field of photon cross-correlation spectroscopy (PCCS) -provides a groundbreaking technology that is based upon dynamic light scattering (DLS) for the analysis of particle sizefrom 0.5 nm to 10,000 nm.

The benefit of PCCS overconventional photon correlation spectroscopy (PCS)is that it accurately measures particle size distributions without the influence of multiple scattered light. As highly concentrated suspensions or emulsions are measured directly, time-consuming sample dilution can be avoided.

With Sympatec’s innovative polarisation-separated backscatter PCCS, NANOPHOX CS takes the proven PCCS to the next level.

Measure up to 100 times higher sample concentration with the NANOPHOX CS than with previous technologies. Image Credit: Sympatec GmbH

Outstanding Performance Features

Sample concentrations up to a hundred times higher |Evaluate the samples directly in their original concentration without dilution

Up to ten times faster measurement times |Measurement results in up to under 1 minute

Enhanced evaluation precision and repeatability

Further PCCS Advantages

A robust method for research, development, and quality control

Extension of conventional PCS offers concurrent measurements of particle size and stability in opaque emulsions andsuspensions

Easy sample preparation without undesired dilution series

Concentration-independent particle characterization by elimination of multiple scattering effects

Insensitive to sample contamination

No need for cleanroom conditions

Direct measurement of agglomeration, stability, and sedimentation of slightly charged (electro-steric stabilized) to uncharged (steric stabilized) particles of turbid samples

Premature detection of invisible destabilization (micro agglomeration) of suspensions or emulsions

Highly sensitive to changes in size and measurement of bimodal distributions

Solid-state measuring technique for in-situ observation of changes in stability or size, e.g., growth and crystallization processes

Analysis of special effects such as particle-particle interactions and changes in viscosity in high-concentrated samples

Wide concentration range by PCS and PCCS united

At the push of a button, the PAQXOS software automatically sets all optimal measurement parameters, verifies the measurability of the sample before starting the analysis, and outputs the signal quality for orientation during and after the measurement. The automatic adjustment of the laser intensity and the accurate positioning of the cuvette to optimize the measurement signal are especially user-friendly.

Acrylic glass, glass, solvent-resistant and micro cuvette. Image Credit: Sympatec GmbH

Typical Applications

Paints and inks

Polymer emulsions

Pharmaceutical emulsions

Oxidized particles (aluminum (II) oxide (AIO) or titanium dioxide (TiO₂)) in suspensions

Research on nanodispersions