Silica Analyzer by PerkinElmer
Constant exposure to silica dust, a class 1 human carcinogen, harms a miner’s health and fu……...
The microDAWN is the only multi-angle light scattering (MALS) detector that can be coupled to any UHPLC-SEC system without loss of resolution. µSEC-MALS determines absolute molecular weight, size and conformation of polymers, peptides, and proteins directly, without resorting to column calibration or reference standards.
Features
Sensitivity: 3.5 ng of 100 kDa polystyrene in THF or 70 ng of BSA in PBS, loaded on a 4.6 x 150 mm UHPLC-SEC column.
Range of molar mass: 200 Da to 10 MDa (may vary with molecular composition, size or solvent)
Range of rms radius Rg: 10 nm to 50 nm
Range of hydrodynamic radius: 0.5 nm to 30 nm (with optional WyattQELS® embedded dynamic light scattering module)
Integrated ultrasonic flow cell cleaning module
Software: ASTRA® chromatography software provides comprehensive analyses and user-friendly features including HPLC control, “One-click MW” and user-designed reports. Optional 21CFR11 support for GMP.
Applications
Proteins: absolute molar mass, size and stoichiometry of monomers, oligomers, complexes, aggregates and fragments.
Glycoproteins, detergent-solubilized membrane proteins, PEGylated proteins, protein-polysaccharide and protein-DNA complexes; heme-containing proteins that absorb laser light
Protein-protein and protein-nucleic acid interactions
Polymers: absolute molar mass and size (distributions and moments), conformation, and branching
Linear or branched polymers, co-polymers
Most aqueous and organic solvents
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