Measuring Fluorescence Lifetime with the DeltaMyc
The DeltaMyc from HORIBA Scientific is a filter-based confocal microscope system capable of measu……...
The Litesizer DLS series classifies nanoparticles and microparticles at the press of a button. These dynamic light scattering devices allow users to identify particles in dispersion as well as peptides or macromolecules in solution across a wide concentration range, reducing sample preparation time.
Litesizer DLS 100
Particle size measurements from the nanometer to the micrometer range
DLS backscatter detection ensures a broad concentration range
Automatic measurement modes
Continuous transmittance measurement
Litesizer DLS 500
Particle characterization from the nanometer to the micrometer range
Particle size measurements using dynamic light scattering at three separate measurement angles
Determination of zeta potential using patented cmPALS
Molecular mass and refractive index measurements
Litesizer DLS 700
Particle characterization from the nanometer to the micrometer range
High resolution of different size populations via multi-angle particle sizing (MAPS)
Determine the concentration of up to three distinct size classes within one sample
Key Features
Benefit from the Perfect Angle Choice – Whatever the Sample
Image Credit: Anton Paar GmbH
Ensure great resolution of diverse size populations using multi-angle particle sizing (MAPS)
To optimize parameter settings, select one of three detection angles (side, rear, or forward scattering)
Manually choose the best angle for the dynamic light scattering device or utilize automatic angle selection.
Benefit from the flexible backscattering angle, which is suitable for turbid samples and eliminates numerous scattering events to provide optimal data quality
Rely on the cmPALS Technique for Zeta Potential Measurements
Image Credit: Anton Paar GmbH
Measure zeta potential using electrophoretic light scattering using the Litesizer DLS 700 and DLS 500
The proprietary cmPALS technology (European Patent 2 735 870) allows for very sensitive readings at low sample concentrations (as low as 0.1 mg/mL)
cmPALS provides quicker measuring times and less sample deterioration
The zeta potential cuvettes include a distinctive Ω-shaped capillary, allowing for extremely reproducible results
Stay Flexible with the Particle Concentration Measurement Mode
Image Credit: Anton Paar GmbH
With the Litesizer DLS 700, users can perform calibration-free particle concentration measurements of up to three distinct size populations inside one sample.
This mode based on single-angle DLS or multi-angle particle sizing (MAPS) ensures the applicability to monodisperse and polydisperse samples across a large concentration range.
Get Continuous Transmittance Measurements for Sample Monitoring
Image Credit: Anton Paar GmbH
Obtain continuous transmittance measurements for sample monitoring
Use automated optimization of measurement parameters (e.g., measurement angle, focus position, duration)
Access data on the commencement of sedimentation or aggregation within a series of measurement
Determine Refractive Index with the Same Instrument
Image Credit: Anton Paar GmbH
Measure the refractive index of the solvent at the precise wavelength and temperature of DLS or ELS measurements (European Patent 3 023 770) using Litesizer DLS 700 and Litesizer DLS 500
Under all experimental circumstances, ensure that particle size and zeta potential results are as accurate as possible.
Use Litesizer DLS 700 and DLS 500 to measure refractive index to within ±0.5% accuracy.
Control the Measurements with Just a Few Clicks
Image Credit: Anton Paar GmbH
Manage data using Kalliope, the user-friendly particle sizing program
The innovative one-page process allows users to see the input parameters, measurement signals, and outcomes at a glance
Quickly evaluate measurement results with established standard reports and organized result overviews
Explore the data using an analysis function, Excel export, and customized report templates
Comply with 21 CFR Part 11
Technical Specifications
Source: Anton Paar GmbH
Litesizer DLS 700 | Litesizer DLS 500 | Litesizer DLS 100 | ||
---|---|---|---|---|
Particle size specifications | ||||
Measurement principle | Dynamic Light Scattering (DLS) | |||
Measuring range | 0.3 nm to 10 μm(particle diameter) | |||
Measurement angles | 15°, 90°, 175°, Multi-angle particle sizing (MAPS) | 15°, 90°, 175° | 175° | |
Min. concentration | 0.1 mg/mL (lysozyme)lower than 0.00001 % (0.1 ppm, Latex 100 nm) | 0.1 mg/mL (lysozyme) | ||
Max. concentration | 50 % w/v (sample-dependent) | |||
Min. sample volume | 12 µL | |||
Accuracy | Better than +/-2 % on NIST traceable standards | |||
Repeatability | Better than +/-2 % on NIST traceable standards | |||
Particle Concentration Specifications | ||||
Analysis model | Mie Theory | - | - | |
Measuring range | 108- 1013particles/mL (sample dependent) | - | - | |
Size limit | 1 µm | - | - | |
Measurement angles | 15°, 90°, 175°, Multi-angle particle sizing (MAPS) | - | - | |
Min. sample volume | 12 µL | - | - | |
Accuracy | +/- 10 % (sample dependent) | - | - | |
Repeatability | +/- 5 % (sample dependent) | - | - | |
Zeta potential specifications | ||||
Measuring principle | Electrophoretic Light Scattering (ELS) / cmPALS | - | ||
Measuring range | >= +/-1000 mV | - | ||
Mobility range | 10-11m²/V.s to 2 x 10-7m²/V.s | - | ||
Size range | 3.8 nm to 100 µm (diameter) | - | ||
Min. sample concentration | 0.1 mg/mL (lysozyme) | - | ||
Max. sample concentration | 70 %w/v (sample-dependent) | - | ||
Max. sample conductivity | 200 mS/cm | - | ||
Min. sample volume | 50 µL (sample-viscosity-dependent) | - | ||
Accuracy | Better than +/-10 % | - | ||
Repeatability | +/-3 % | - | ||
Molecular mass specifications | ||||
Measuring principle | Static Light Scattering (SLS) | - | ||
Measuring range (mass) | 300 Da to 20 MDa | - | ||
Measuring range (particle size) | Up to 40 nm (diameter) | - | ||
Measurement angle | 90° | - | ||
Min. sample concentration | 0.1 mg/mL (lysozyme) | - | ||
Accuracy | +/-10 % | - | ||
Repeatability | +/-5 % | - | ||
Transmittance specifications | ||||
Measuring range | 0 % to 100 % | |||
Min. sample volume | 15 µL | |||
Accuracy | Better than +/-1 % | |||
Refractive index specifications | ||||
Measuring range | 1.28 to 1.50 | - | ||
Min. sample volume | 1 mL | - | ||
Accuracy | +/-0.5 % | - | ||
General specifications | ||||
Light source | Semiconductor laser diode / 40 mW, 658 nm | |||
Laser warm-up time | 6 min | |||
Temperature control range | 0 °C to 90 °C | |||
Ambient operating temperature | 10 °C to 35 °C | |||
Humidity | Up to 80 % non-condensing | |||
Dimensions (W, D, H) | 460 mm, 485 mm, 135 mm | |||
Weight | Approx. 18 kg (40 lb) | Approx. 16.3 kg (36 lb) |
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