Dispersibility and Stability with the Turbiscan DNS

上海仪舶实验室自动化 25-01-23 15:10:56

Dispersibility and Stability with the Turbiscan DNS

TURBISCAN DNS from Microtracis the first user-friendly platform for stability and dispersibility studies. Dispersibility studies can be executed, while processing the dispersion (at flow) and on the native samples (no added forces, no dilution) through Static Multiple Light Scattering (SMLS), as recommended by the ISO TS 21357.

The flow studies can be performed by either pumping the sample from the process or reactor (circulation function of the Turbiscan DNS: T-LOOP) or by mixing directly in the measurement cell (mixing function: T-MIX).

The stability measurement is performed at rest and the Turbiscan DNS provides a quick (up to 200 times quicker), quantitativeand dependable stability measurement of destabilization kinetics in the absence of dilution or mechanical forces.

Highlights of TURBISCAN DNS

Online Particle Sizing

Direct particle size reduction kinetics are done while mixing or during the process through combined functions: T-MIX and T-LOOP. The Turbiscan DNS provides high-frequency measurement (up to 10/second) to accurately track the impact of the mixing parameters.

Fast and Quantified Shelf-Life

The SMLS has extreme sensitivity (ranging up to 200x times quicker compared to the naked eye). Aside frombeing quick, Turbiscan stability measurement also offers the destabilization mechanism and measures them with the one-click TSI or more in-depth parameters (aggregation speed, migration kinetic).

Measurement of Dispersibility and Stability

Quantified dispersion stability

Online Mean Particle Size

Shelf life andlong term stability analysis

Mean diameter

Aggregation andagglomeration kinetics

Migration velocity

Volume fraction

Dispersibility ratio

2 in 1 Formulation Platform

The SMLS provides a huge application range concerning particle size (from 10 nm to mm) and concentration (from 10-4 to 95%v/v). Dispersibility and stability studies are also executed in the absence of dilution.

Applications

General chemistry and polymers

Pharmaceutical

Paint and inks

Electronics

Food and beverages

Oil and Petroleum

Technical Features

Source: Microtrac

Technology SMLS 880 nm
Sample Cell Volume 4 or 20 ml
Measurement while process YES : Mixing & Circulation
Temperature range RT - 60 °C
Number of Samples 1
Maximum sample conc. 95% v/v
Measured size range 10 nm - 1 mm
Reproducibility / Repeatability 0.1 % / 0.05%
Acquisition scan step 40 µm
Maximum measurement frequency 10 measurements/s
ISO Compliance TR13097 TR18811 TR13014 TS21357
Dimensions 70 x 63 x 52 cm
Weight 35 kg

Key Benefits

TURBISCAN is the world reference technology for physical stability analysis. With the availability of seamless sample preparation, intuitive software, and highly reliable measurements, the Turbiscan DNS is currently opening a playground for dispersibility studies and setting a new reference.

The instrument measures Dispersibility and Stability, and all the tools and accessories provided and combineto save time and make the measurement ready to play: Sample - Close the cap - Click.

Turbiscan DNS has been developed to function with 20 mL disposable glass cells (comes with 4 mL cells for stability measurement).

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