DECTRIS SINGLA® Fast and Most Sensitive Hybrid-Pixel Detector

The DECTRIS SINGLA^® detector is a high-speed, hybrid-pixel electron-counting camera designed for Life Sciences applications. With a sensitive area of approximately 1000 × 1000 pixels, it is appropriate for cryo-electron microscopy (cryoEM) and micro-electron diffraction (microED) applications. Experiments like single-particle analysis and cryo-electron tomography benefit substantially from the detector’s speed.

The SINGLA detector's rapid readout speed (more than 2000 frames per second) and wide dynamic range make it excellent for small-molecule and 3D micro-crystallography applications. The bottom-mounted detector works with JEOL and Thermo Fisher Scientific transmission electron microscopes (TEM).

Fast and Accurate: The detector’s direct electron detection at a high frame rate allows optimal data quality at lower energy (100 keV), enabling low-dose electron microscopy.

Compatible: The DECTRIS SINGLA^®detector is compatible with the SerialEM software.

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Detector Specifications

Source: Dectris Ltd

Case Study

A purpose-built electron cryo-microscope with DECTRIS SINGLA that operates at 100 keV promises to lower the cost and complexity of biological structure research.

Published by Greg McMullan et al.. The Proceedings of the National Academy of Sciences 120.49 (2023): e2312905120 “Structure determination by cryoEM at 100 keV.”

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Techniques

Cryo-Electron Microscopy (cryoEM)

Image Credit: Dectris Ltd

DECTRIS detectors allow users to get the most information aboutthe structure of a biological molecule while minimizing radiation harm.

Micro-Electron Diffraction (microED)

Image Credit: Dectris Ltd

Quick, radiation-hard, hybrid-pixel electron detectors are used to capture all of the data from the samples.