AutoMATE 4: A Linear 4 Reactor, Bench-Top, Automated Parallel Synthesis Platform

The AutoMATE 4 is a highly versatile, linear, 4-reactor, automated parallel synthesis platform, for use in general chemical synthesis within R&D and process development, as well asmore bespoke applications. As with the PolyBLOCK 4, the four independently controlled reaction zones make AutoMATE 4 especially well-suited for DoE campaigns and the platform’s modular design allows for an easy expansion of capabilities. In particular, the linear reactor design of the AutoMATE 4 makes it ideal for more demanding applications, such as where multiple inputs and outputs are required.

Application modules that can be added include:

Solubility/crystallization monitoring

Online calorimetry option

Catalyst screening

The platform supports reactor volumes of up to 500 ml per reactor and is equipped with adaptors to support a range of reactor types and sizes, including integration with H.E.L’s catalyst screening CAT reactor blocks. Additional functionality modules include:

Liquid dosing

Gas feed

Liquid sampling, including integration with the ASU

Quick-connect refluxing option

Quick-connect inerting solution

pH monitoring

Features and Options:

Temperature Control

Ambient to 250 ⁰C (without external cooling).

Options to increase the range of -40 ⁰C (circulator dependent) or up to 350 ⁰C.

A separate mantle around each reactor allows the temperature to be controlled individually.

With arange/difference of over 100 °C between the reactors.

Independent Stirring

Indirect agitation with suspended magnetic stirringas standard.

• Suspended agitation for efficient mixing on small-scale and non-viscous samples.

• The more spacious 'suspended'stirrers are suitablefor slurries.

• Optional Overhead direct agitation for larger vessels.

  Intelligent Software Control and Analysis

  labCONSOL software control enables regular data logging, multi-step recipes, parameter control, and feedback loops. The software adds a responsive intelligence to the AutoMATE 4 system and still delivers an intuitive interface that needs only minimal training to run quickly.

  Safety Features

  Include automatic user-configurable reaction detection and shutdown procedures, to ensure user safety.

  Automatic hardware and software fail-safes are installed on every system.

  Condenser options

  • Easy quick-connect solution for condensing and inerting in larger reactors. Seals allow condensers to be removed without cooling liquid spillage.

    Also available reflux and inerting block, with adapters for vials, tubes, and reactors

    Reactor Options

    Vessel typesare available in Glass, Stainless Steel, orHastelloy. With reactorvolumes up to 500 ml

    High Pressure and Vacuum Systemsavailable, more details on our high-pressure system can be found on thehigh-pressure variant

    Sampling Systemsthrough active pumps, manual dip tubes, automated level control, or multisampling units, like theASU

    Reagent Additionthrough fully automated liquidand gas feeds as well as volumetric syringe pumps. These solutions can be applied to both high and low-pressure systems.

    Control Optionsall relevant inputs can be logged, enabling automated monitoring and, where appropriate, feedback control of the reactor system

    Sensor Options

    Temperature, pressure, pH, turbidity, conductivity

    Integration of third-party probes is possible, such as in-situ FTIR, particle sizing probes, and Raman probes.