Carlisle Companies Inc.
Carlisle's is a diversified global manufacturing company whose product lines serve the const……...
英国Phico Therapeutics
Phico Therapeutics 是一家生物技术公司，正在开发一种新型平台技术，该公司相信这项技术可以为克服细菌耐药性的新一代抗生素奠定基础。
我们的 SASPjecttrade； 平台利用工程细菌病毒（噬菌体）将被称为小酸溶性孢子蛋白（SASP）的全谱抗菌蛋白递送至选定的细菌种类。SASPjecttrade； 的工作原理是将编码 SASP 的基因直接注射到目标细菌中。注射的基因会指示目标细菌产生 SASP，然后 SASP 会与细菌 DNA 结合并使其失活。SASP 会“关闭”DNA，使目标细菌细胞无法代谢或繁殖。然后，免疫系统可以将细菌从体内清除。
SASP 可以与所有细菌 DNA 结合，无论 DNA 序列如何。DNA 的自发突变，或输入新的 DNA 并赋予细菌细胞新的特性，是细菌产生抗生素耐药性的关键途径。这两种策略都不会影响 SASP 结合和灭活细菌 DNA 的能力。
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